Cardio ThinkLab

Screening & Diagnosis of Heart Failure in Pre-Diabetic and Diabetic Patients

The burden of CVD in Diabetic Patients in APAC

Prevalence of Cardiovascular Disease (CVD) among Type 2 diabetes mellitus (T2DM) patients1

T2DM is associated with a twofold increased risk of CVD vs non-T2DM patients1

Pre-Diabetic and Diabetic Patients at risk of Heart Failure


High risk for HF

  • Obesity
  • Hypertension
  • Hyperlipidemia
  • Diabetic Kidney Disease
  • Coronary Artery Disease
  • Sex
  • Social Determinants of Health
  • Duration of Diabetes
  • Uncontrolled Hypertension

Cardiac Structural Abnormality/ Dysfunction

  • LV systolic dysfunction
  • LV diastolic dysfunction
  • LV hypertrophy
  • Chamber enlargement
  • Valvular disease
  • Increased filling pressures OR Elevated biomarkers


  • NT-proBNP (≥125 pg/mL)
  • BNP (≥50 pg/mL)
  • High Sensitive Cardiac Troponin
    (>99th per-centile upper reference limit)



in at least 1 year

(CXR, Echocardiogram)

By utilising cardiac biomarkers, identifying high-risk and early-stage heart failure in patients with T2DM enables timely intervention to prevent or delay the advancement of heart failure.2

Updates from Leading Experts

STRONG-HF: Post-discharge Heart Failure Management and Implementation of GDMT Heart Failure Therapy

Prof Alexandre Mebazaa shares the key results and highlights from the STRONG-HF study that assessed the safety, tolerability of optimization of guideline directed medical therapy. [...]


CANVAS study: NT-proBNP and CVD risk reduction

Can you give us a short description of the CANVAS program? The CANVAS program was a set of two trials, whose goal was to evaluate the role of an SGLT2...

1 July 2021
Dr James L Januzzi