Dr David Sim
Cardiologist, Heart Failure Program Director, National Heart Center Singapore; Immediate past president of Heart Failure Society (Singapore)

Dr David Sim’s Clinical Cases: NT-proBNP in Heart Failure Patients

Click on one of the 3 tabs below to switch between different type of heart failure patients


53-Year old-Women


Key signs and symptoms

Acute decompensated heart failure requiring admission
for intravenous diuretic – LVEF 25%


Medical history

Diabetes mellitus for the last 3 years
Chronic heart failure for the last 2 years


Clinical examination

BP 120/80 mmHg
Heart rate 72/min
Pulmonary congestion with pedal edema
Potassium 4.2 mmol/L
Creatinine 90 Umol/L,
HbA1c 7.1%



Enalapril 10 mg bid
Bisoprolol 10 mg od
Spironolactone 25 mg od
Ivabradine 5 mg bid
Loop diuretic
Metformin 500 mg bid
Empagliflozin 10 mg od

Use of NT-proBNP for hospitalized heart failure patients

Was the repeated NT-proBNP before discharge result useful?

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