Dr Evangelos Giannitsis
Cardiologist, Medical Director of Chest Pain Unit, University Hospital of Heidelberg, Germany

hs-TnT Rapid Diagnosis of AMI- ESC 0h/3h Algorithm


  • European Society of Cardiology (ESC) guidelines recommend the 0h/3 h algorithm for Acute Myocardial Infarction (AMI) if high-sensitivity Troponin is available
  • Serial testing is obligatory if troponin has a rise and / or fall kinetic pattern
  • For diagnosis of AMI, patients presenting with normal troponin, a change of 50% from Upper Reference Limit (URL) is recommended, a relative change of +/- 20% is recommended if there is an elevation of troponin at baseline
  • Recommended thresholds and delta changes are assay specific

Updates from Leading Experts

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Prof Alexandre Mebazaa shares the key results and highlights from the STRONG-HF study that assessed the safety, tolerability of optimization of guideline directed medical therapy. [...]


CANVAS study: NT-proBNP and CVD risk reduction

Can you give us a short description of the CANVAS program? The CANVAS program was a set of two trials, whose goal was to evaluate the role of an SGLT2...

1 July 2021
Dr James L Januzzi