Dr Januzzi: Analyses shows that obesity did not affect the prognostic meaning of the 30% reduction during hospitalisation. Although obesity suppresses natriuretic peptide, when an obese patient is admitted for heart failure, they usually have elevated values. It is just that they are not as high as one might expect. The reduction is largely the same.
The decrease of NT-proBNP, 30% or more, from admission to discharge indicates the patient will have a better prognosis. For the obese patient, can we use the same logic?
11 March 2021